KERA antibody (C-Term) (HRP)

Catalog No. ABIN8004274

The HRP-conjugated Rabbit Polyclonal anti-KERA antibody (ABIN8004274) specifically detects KERA in WB, IHC and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for KERA antibody (C-Term) (HRP) (ABIN8004274)

Target: KERA (Keratocan (KERA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KERA antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-KERA Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-Keratocan Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Keratocan, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KERA

Target: KERA (Keratocan (KERA))

Alternative Name: KERA

Background:

Background: Keratocan (KTN), also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. It is mapped to 12q22. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). Keratan sulfate proteoglycans (KSPGs) are members of the small leucine-rich proteoglycan (SLRP) family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of the cornea.

Gene Full Name: keratocan

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Gene ID: 11081

UniProt: O60938

Pathways: Glycosaminoglycan Metabolic Process