KERA antibody (C-Term) (PE)

Catalog No. ABIN8004276

The Rabbit Polyclonal anti-KERA antibody is suitable to detect KERA in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for KERA antibody (C-Term) (PE) (ABIN8004276)

Target: KERA (Keratocan (KERA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KERA antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-KERA Antibody (PE)

Binding Specificity: C-Term

Purpose: Anti-Keratocan Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Keratocan, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for KERA

Target: KERA (Keratocan (KERA))

Alternative Name: KERA

Background:

Background: Keratocan (KTN), also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. It is mapped to 12q22. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). Keratan sulfate proteoglycans (KSPGs) are members of the small leucine-rich proteoglycan (SLRP) family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of the cornea.

Gene Full Name: keratocan

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Gene ID: 11081

UniProt: O60938

Pathways: Glycosaminoglycan Metabolic Process