KERA antibody (C-Term)

Catalog No. ABIN8004278

This Rabbit Polyclonal antibody specifically detects KERA in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for KERA antibody (C-Term) (ABIN8004278)

Target: KERA (Keratocan (KERA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KERA antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-KERA Antibody

Binding Specificity: C-Term

Purpose: Anti-Keratocan Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by two amino acids.

Characteristics: Anti-Keratocan Antibody. Tested in WB applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Keratocan, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for KERA

Target: KERA (Keratocan (KERA))

Alternative Name: KERA

Background:

Background: Keratocan (KTN), also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. It is mapped to 12q22. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2). Keratan sulfate proteoglycans (KSPGs) are members of the small leucine-rich proteoglycan (SLRP) family. KSPGs, particularly keratocan, lumican and mimecan, are important to the transparency of the cornea.

Gene Full Name: keratocan

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Molecular Weight: 50 kDa

Gene ID: 11081

UniProt: O60938

Pathways: Glycosaminoglycan Metabolic Process