KLF3 antibody (N-Term) (FITC)

Catalog No. ABIN8004703

The FITC-conjugated Rabbit Polyclonal anti-KLF3 antibody (ABIN8004703) specifically detects KLF3 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for KLF3 antibody (N-Term) (FITC) (ABIN8004703)

Target: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF3 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-KLF3 Antibody (FITC)

Binding Specificity: N-Term

Purpose: Anti-Krueppel-like factor 3 KLF3 Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related rat sequence by one amino acid,and from the related mouse sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human KLF3, different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for KLF3

Target: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Alternative Name: KLF3

Background:

Background: KLF3 (Krueppel-like factor 3) is a protein that in humans is encoded by the KLF3 gene. It is also known as BKLF (Basic kruppel-like factor). KLF3 is a member of the Krüppel-like factors family of transcription factors. KLF3 primarily represses transcription through the transcriptional corepressor C-terminal binding protein (CtBP). Suske et al. (2005) stated that the human KLF3 gene maps to chromosome 4p14, and the mouse Klf3 gene maps to chromosome 5C3.3. Suske et al. (2005) stated that the human and mouse KLF3 proteins contain 345 and 344 amino acids, respectively. Both have a characteristic zinc finger domain, but lack the N-terminal buttonhead box found in related SP transcription factors. The repression mediated through KLF3 is also partially dependent on the sumoylation of its K10 and K197. Within KLF3's C-terminal, which is highly conserved throughout the KLF family, resides three C2H2 zinc fingers that preferentially bind the site NRG GNG NGR.

Gene Full Name: KLF transcription factor 3

Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.

Gene ID: 51274

UniProt: P57682