KLF4 antibody (AA 196-384) (Fluoro647)

Catalog No. ABIN8004740

This Rabbit Polyclonal antibody specifically detects KLF4 in FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for KLF4 antibody (AA 196-384) (Fluoro647) (ABIN8004740)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF4 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-KLF4 Antibody (Fluoro647)

Binding Specificity: AA 196-384

Purpose: Anti-Klf4 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Mouse Klf4 shares 72.6% amino acid (aa) sequence identity with human KLF4.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Klf4 recombinant protein (Position: F196-K384). Mouse Klf4 shares 72.6% amino acid (aa) sequence identity with human KLF4.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: Klf4

Background:

Background: Kruppel-like factor 4, also known as EZF or GKLF, is a protein that in humans is encoded by the KLF4 gene. This gene is mapped to 9q31.2. KLF4 gene encodes a member of the Kruppel family of transcription factors. This gene plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. It is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. This gene involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.

Gene Full Name: Kruppel-like transcription factor 4 (gut)

Gene ID: 16600

UniProt: Q60793

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance