Lactate Dehydrogenase A antibody (AA 2-106) (Fluoro488)

Catalog No. ABIN8004909

The Rabbit Polyclonal anti-Lactate Dehydrogenase A antibody is suitable to detect Lactate Dehydrogenase A in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for Lactate Dehydrogenase A antibody (AA 2-106) (Fluoro488) (ABIN8004909)

Target: Lactate Dehydrogenase A (LDHA)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lactate Dehydrogenase A antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Lactate Dehydrogenase A Antibody (Fluoro488)

Binding Specificity: AA 2-106

Purpose: Anti-LDHA Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human LDHA recombinant protein (Position: A2-R106). Human LDHA shares 94.3% amino acid (aa) sequence identity with both mouse,rat LDHA.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human LDHA recombinant protein (Position: A2-R106). Human LDHA shares 94.3% amino acid (aa) sequence identity with both mouse and rat LDHA.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Lactate Dehydrogenase A

Target: Lactate Dehydrogenase A (LDHA)

Alternative Name: LDHA

Background:

Background: Lactate dehydrogenase A, also known as LDHA, is an enzyme which in humans is encoded by the LDHA gene. The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.

Gene Full Name: lactate dehydrogenase A

Gene ID: 3939

UniProt: P00338

Pathways: Warburg Effect