LDHD antibody (AA 56-498) (Fluoro488)

Catalog No. ABIN8004931

The Fluoro488-conjugated Rabbit Polyclonal anti-LDHD antibody (ABIN8004931) specifically detects LDHD in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for LDHD antibody (AA 56-498) (Fluoro488) (ABIN8004931)

Target: LDHD (Lactate Dehydrogenase D (LDHD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDHD antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-LDHD Antibody (Fluoro488)

Binding Specificity: AA 56-498

Purpose: Anti-LDHD Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LDHD recombinant protein (Position: R56-Q498).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LDHD

Target: LDHD (Lactate Dehydrogenase D (LDHD))

Alternative Name: LDHD

Background:

Background: Two naturally occurring forms of lactate dehydrogenase with similar but unique substrate specificities have been isolated in lower organisms including invertebrates, fungi, and prokaryotes. These dehydrogenase enzymes are L-lactate dehydrogenase and D-lactate dehydrogenase (LDHD) that are specific to the L and D isomers of lactate, respectively (PMID: 12127981). In lactic acid bacteria, LDHD plays a key role in anaerobic energy metabolism (PMID: 497162). Despite the identification of D-lactate and other D-2-hydroxyacids in prokaryotes, and the obvious connections and similarities to vertebrate metabolic pathways, very few mammalian D-2-hydroxyacid dehydrogenases have been found. LDHD has 2 isoforms with the molecular weight of 52 and 54 kDa, and can be detected as 45-54 kDa.

Gene Full Name: lactate dehydrogenase D

Gene ID: 197257

UniProt: Q86WU2

Pathways: Ribonucleoside Biosynthetic Process