Lamin B Receptor antibody (AA 102-209) (Fluoro647)

Catalog No. ABIN8005004

This Rabbit Polyclonal antibody specifically detects Lamin B Receptor in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Lamin B Receptor antibody (AA 102-209) (Fluoro647) (ABIN8005004)

Target: Lamin B Receptor (LBR)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B Receptor antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Lamin B Receptor Antibody (Fluoro647)

Binding Specificity: AA 102-209

Purpose: Anti-Lamin B Receptor/LBR Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Lamin B Receptor/LBR recombinant protein (Position: H102-F209).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Lamin B Receptor

Target: Lamin B Receptor (LBR)

Alternative Name: LBR

Background:

Background: Lamin-B receptor is a protein, and in humans, it is encoded by the LBR gene. It is mapped to 1q42.12. The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Gene Full Name: lamin B receptor

Gene ID: 3930

UniProt: Q14739