LLGL2 antibody (AA 102-553) (HRP)

Catalog No. ABIN8005418

This Rabbit Polyclonal antibody specifically detects LLGL2 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for LLGL2 antibody (AA 102-553) (HRP) (ABIN8005418)

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LLGL2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-LLGL2 Antibody (HRP)

Binding Specificity: AA 102-553

Purpose: Anti-LLGL2 Antibody HRP Conjugated

Predicted Reactivity: Human LLGL2 shares 91.2% amino acid (aa) sequence identity with mouse LLGL2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LLGL2 recombinant protein (Position: L102-Q553). Human LLGL2 shares 91.2% amino acid (aa) sequence identity with mouse LLGL2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LLGL2

Target: LLGL2 (Lethal Giant Larvae Homolog 2 (LLGL2))

Alternative Name: LLGL2

Background:

Background: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: LLGL scribble cell polarity complex component 2

Gene ID: 3993

UniProt: Q6P1M3

Pathways: WNT Signaling