LINGO2 antibody (AA 28-513)

Catalog No. ABIN8005455

The Rabbit Polyclonal anti-LINGO2 antibody is suitable to detect LINGO2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for LINGO2 antibody (AA 28-513) (ABIN8005455)

Target: LINGO2 (Leucine Rich Repeat and Ig Domain Containing 2 (LINGO2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-LINGO2 Antibody

Binding Specificity: AA 28-513

Purpose: Anti-LINGO2 Antibody

Predicted Reactivity: Human LINGO2 shares 97.9% amino acid (aa) sequence identity with mouse LINGO2.

Characteristics: Anti-LINGO2 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LINGO2 recombinant protein (Position: C28-R513). Human LINGO2 shares 97.9% amino acid (aa) sequence identity with mouse LINGO2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LINGO2

Target: LINGO2 (Leucine Rich Repeat and Ig Domain Containing 2 (LINGO2))

Alternative Name: LINGO2

Background:

Background: Leucine rich repeat and Ig domain containing 2 is a protein that in humans is encoded by the LINGO2 gene. LINGO-2 (LRR and Ig domain-containing, Nogo Receptor-interacting protein 2, also LRRN6C and LERN3), is a member of the LRR transmembrane (TM) protein family. LINGO-2 is thought to function outside the CNS with little involvement by p75/NgR1. The human LINGO-2 precursor is a 606 amino acid (aa) type I TM protein that contains a large extracellular domain and a short cytoplasmic tail. The human LINGO-2 precursor is 99 % and 98 % aa identical to dog and mouse LINGO-2, respectively.

Gene Full Name: leucine rich repeat and Ig domain containing 2

Molecular Weight: 68 kDa

Gene ID: 158038

UniProt: Q7L985