LRRC40 antibody (AA 21-598) (Biotin)

Catalog No. ABIN8005512

The Rabbit Polyclonal anti-LRRC40 antibody is suitable to detect LRRC40 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IHC.

Quick Overview for LRRC40 antibody (AA 21-598) (Biotin) (ABIN8005512)

Target: LRRC40 (Leucine Rich Repeat Containing 40 (LRRC40))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC40 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LRRC40 Antibody (Biotin)

Binding Specificity: AA 21-598

Purpose: Anti-LRRC40 Antibody Biotin Conjugated

Predicted Reactivity: Human LRRC40 shares 84.1% amino acid (aa) sequence identity with mouse LRRC40.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LRRC40 recombinant protein (Position: R21-D598). Human LRRC40 shares 84.1% amino acid (aa) sequence identity with mouse LRRC40.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LRRC40

Target: LRRC40 (Leucine Rich Repeat Containing 40 (LRRC40))

Alternative Name: LRRC40

Background:

Background: Leucine rich repeat containing 40 (LRRC40) is a protein that in humans is encoded by the LRRC40 gene. The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic α/β horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC40 (leucine rich repeat containing 40) is a 602 amino acid protein that contains 20 LRR (leucine-rich) repeats.

Gene Full Name: leucine rich repeat containing 40

UniProt: Q9H9A6