LZIC antibody (AA 81-1080) (Fluoro488)

Catalog No. ABIN8005614

The Rabbit Polyclonal anti-LZIC antibody is suitable to detect LZIC in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for LZIC antibody (AA 81-1080) (Fluoro488) (ABIN8005614)

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZIC antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-LZIC Antibody (Fluoro488)

Binding Specificity: AA 81-1080

Purpose: Anti-LZIC Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human IMPG2 shares 70.8%,72% amino acid (aa) sequence identity with mouse,rat IMPG2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IMPG2 recombinant protein (Position: R81-R1080). Human IMPG2 shares 70.8% and 72% amino acid (aa) sequence identity with mouse and rat IMPG2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LZIC

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Alternative Name: LZIC

Background:

Background: LZIC is closely related to ICAT, a physiological inhibitor ofthe Wnt pathway that interacts physically and functionally withβ-catenin to prevent the transcription ofWnt target genes. LZIC'sICAT-homologousregion is highly similarto ICAT with particular conservation ofresiduesthat are used by ICAT forβ-catenin-binding. LZIC does not interactwithβ-catenin in vitro orin vivo. LZIC is a protein conserved in vertebrates, isrequired for neuronal survival.

Gene Full Name: leucine zipper and CTNNBIP1 domain containing

Gene ID: 84328

UniProt: Q8WZA0