LZIC antibody (AA 81-1080) (PE)

Catalog No. ABIN8005620

The Rabbit Polyclonal anti-LZIC antibody is suitable to detect LZIC in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IF, IHC, FACS, ICC and IP.

Quick Overview for LZIC antibody (AA 81-1080) (PE) (ABIN8005620)

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZIC antibody is conjugated to PE

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-LZIC Antibody (PE)

Binding Specificity: AA 81-1080

Purpose: Anti-LZIC Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human IMPG2 shares 70.8%,72% amino acid (aa) sequence identity with mouse,rat IMPG2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IMPG2 recombinant protein (Position: R81-R1080). Human IMPG2 shares 70.8% and 72% amino acid (aa) sequence identity with mouse and rat IMPG2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LZIC

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Alternative Name: LZIC

Background:

Background: LZIC is closely related to ICAT, a physiological inhibitor ofthe Wnt pathway that interacts physically and functionally withβ-catenin to prevent the transcription ofWnt target genes. LZIC'sICAT-homologousregion is highly similarto ICAT with particular conservation ofresiduesthat are used by ICAT forβ-catenin-binding. LZIC does not interactwithβ-catenin in vitro orin vivo. LZIC is a protein conserved in vertebrates, isrequired for neuronal survival.

Gene Full Name: leucine zipper and CTNNBIP1 domain containing

Gene ID: 84328

UniProt: Q8WZA0