LZIC antibody (AA 81-1080)
Quick Overview for LZIC antibody (AA 81-1080) (ABIN8005622)
Target
See all LZIC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
-
-
Binding Specificity
- AA 81-1080
-
Purpose
- Anti-LZIC Antibody
-
Cross-Reactivity (Details)
- No cross reactivity with other proteins.
-
Predicted Reactivity
- Human IMPG2 shares 70.8%,72% amino acid (aa) sequence identity with mouse,rat IMPG2,respectively.
-
Characteristics
- Anti-LZIC Antibody. Tested in ELISA, IP, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
-
Purification
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human IMPG2 recombinant protein (Position: R81-R1080). Human IMPG2 shares 70.8% and 72% amino acid (aa) sequence identity with mouse and rat IMPG2, respectively.
-
Isotype
- IgG
-
-
-
-
Application Notes
- Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
-
-
- LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))
-
Alternative Name
- LZIC
-
Background
-
Background: LZIC is closely related to ICAT, a physiological inhibitor ofthe Wnt pathway that interacts physically and functionally withβ-catenin to prevent the transcription ofWnt target genes. LZIC'sICAT-homologousregion is highly similarto ICAT with particular conservation ofresiduesthat are used by ICAT forβ-catenin-binding. LZIC does not interactwithβ-catenin in vitro orin vivo. LZIC is a protein conserved in vertebrates, isrequired for neuronal survival.
Gene Full Name: leucine zipper and CTNNBIP1 domain containing
-
Molecular Weight
- 21 kDa
-
Gene ID
- 84328
-
UniProt
- Q8WZA0
Target
-