LRIG3 antibody (Middle Region) (PE)

Catalog No. ABIN8005796

This Rabbit Polyclonal antibody specifically detects LRIG3 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for LRIG3 antibody (Middle Region) (PE) (ABIN8005796)

Target: LRIG3 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 3 (LRIG3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRIG3 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-LRIG3 Antibody (PE)

Binding Specificity: Middle Region

Purpose: Anti-LRIG3 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human LRIG3, different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LRIG3

Target: LRIG3 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 3 (LRIG3))

Alternative Name: LRIG3

Background:

Background: LRIG3 (leucine-rich repeats and Ig-like domains-3) is a 140 kDa type I transmembrane glycoprotein member of the mammalian LRIG glycoprotein family. It shares 46.8 % and 54.0 % amino acid identity with LRIG1 and LRIG2, respectively, with highest conservation in the extracellular, transmembrane, and membrane-proximal sequences. This gene is mapped to chromosome 12q13.2. LRIG3 may play a role in craniofacial and inner ear morphogenesis during embryonic development. It also may act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1.

Gene Full Name: leucine rich repeats and immunoglobulin like domains 3

Gene ID: 121227

UniProt: Q6UXM1