LMO1 antibody (C-Term) (Fluoro488)

Catalog No. ABIN8006076

The Rabbit Polyclonal anti-LMO1 antibody is suitable to detect LMO1 in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for LMO1 antibody (C-Term) (Fluoro488) (ABIN8006076)

Target: LMO1 (LIM Domain Only 1 (Rhombotin 1) (LMO1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMO1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-LMO1 Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-LMO1 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LMO1, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LMO1

Target: LMO1 (LIM Domain Only 1 (Rhombotin 1) (LMO1))

Alternative Name: LMO1

Background:

Background: Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene. This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions, thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.

Gene Full Name: LIM domain only 1

Gene ID: 4004

UniProt: P25800

Pathways: Dopaminergic Neurogenesis