LIN28A antibody (AA 3-209) (Fluoro488)

Catalog No. ABIN8006165

This Rabbit Polyclonal antibody specifically detects LIN28A in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LIN28A antibody (AA 3-209) (Fluoro488) (ABIN8006165)

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIN28A antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-LIN28A Antibody (Fluoro488)

Binding Specificity: AA 3-209

Purpose: Anti-Lin28/LIN28A Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Lin28/LIN28A recombinant protein (Position: S3-N209).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LIN28A

Target: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Alternative Name: LIN28A

Background:

Background: Protein lin-28 homolog A is a protein that in humans is encoded by the LIN28A gene. It is mapped to 1p36.11. This gene encodes a < a href=https://www.bosterbio.com/anti-protein-lin-28-homolog-b-lin28b-antibody-a00896-boster.html style=color:#EA8D28>LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.

Gene Full Name: lin-28 RNA binding posttranscriptional regulator A

Gene ID: 79727

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance