LIN28B antibody (AA 23-249) (FITC)

Catalog No. ABIN8006179

The FITC-conjugated Rabbit Polyclonal anti-LIN28B antibody (ABIN8006179) specifically detects LIN28B in FACS. The antibody is reactive with Human samples.

Quick Overview for LIN28B antibody (AA 23-249) (FITC) (ABIN8006179)

Target: LIN28B (Lin-28 Homolog B (LIN28B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIN28B antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-LIN28B Antibody (FITC)

Binding Specificity: AA 23-249

Purpose: Anti-LIN28B Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LIN28B recombinant protein (Position: E23-K249).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LIN28B

Target: LIN28B (Lin-28 Homolog B (LIN28B))

Alternative Name: LIN28B

Background:

Background: The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.

Gene Full Name: lin-28 RNA binding posttranscriptional regulator B

Gene ID: 389421

UniProt: Q6ZN17