Lipin 1 antibody (AA 90-886) (APC)

Catalog No. ABIN8006313

The Rabbit Polyclonal anti-Lipin 1 antibody is suitable to detect Lipin 1 in samples from Human and Rat. It has been validated for FACS.

Quick Overview for Lipin 1 antibody (AA 90-886) (APC) (ABIN8006313)

Target: Lipin 1 (LPIN1)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipin 1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Lipin 1 Antibody (APC)

Binding Specificity: AA 90-886

Purpose: Anti-Lipin 1/LPIN1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Lipin 1/LPIN1 recombinant protein (Position: Q90-H886).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Lipin 1

Target: Lipin 1 (LPIN1)

Alternative Name: LPIN1

Background:

Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, acute recurrent rhabdomyolysis, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes.

Gene Full Name: lipin 1

Gene ID: 23175

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process