Lipocalin 2 antibody (AA 21-198) (HRP)

Catalog No. ABIN8006345

This Rabbit Polyclonal antibody specifically detects Lipocalin 2 in WB, ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Lipocalin 2 antibody (AA 21-198) (HRP) (ABIN8006345)

Target: Lipocalin 2 (LCN2)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipocalin 2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Lipocalin 2 Antibody (HRP)

Binding Specificity: AA 21-198

Purpose: Anti-Lipocalin 2/LCN2 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived rat Lipocalin 2 recombinant protein (Position: Q21-N198). Rat Lipocalin 2 shares 64.4 %,81.1 % amino acid (aa) sequence identity with human,mouse Lipocalin 2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived rat Lipocalin 2 recombinant protein (Position: Q21-N198). Rat Lipocalin 2 shares 64.4 % and 81.1 % amino acid (aa) sequence identity with human and mouse Lipocalin 2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Lipocalin 2

Target: Lipocalin 2 (LCN2)

Alternative Name: Lcn2

Background:

Background: Europhile gelatinase-associated lipocalin (NGAL) is a protein that in humans is encoded by the LCN2 gene. The binding of lipocalin-2 to bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor.

Gene Full Name: lipocalin 2

Sequence Similarities: Belongs to the KIN17 family.

Gene ID: 170496

UniProt: P30152

Pathways: Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis