PLA2G7 antibody (AA 176-415) (FITC)

Catalog No. ABIN8006464

The FITC-conjugated Rabbit Polyclonal anti-PLA2G7 antibody (ABIN8006464) specifically detects PLA2G7 in FACS. The antibody is reactive with Human samples.

Quick Overview for PLA2G7 antibody (AA 176-415) (FITC) (ABIN8006464)

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G7 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-PLA2G7 Antibody (FITC)

Binding Specificity: AA 176-415

Purpose: Anti-PAFAH/PLA2G7 Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human PAFAH recombinant protein (Position: A176-N415).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PLA2G7

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Alternative Name: PLA2G7

Background:

Background: Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme that in humans is encoded by the PLA2G7 gene. Lp-PLA2 is a 45- kDa protein of 441 amino acids. It is one of several PAF acetylhydrolases. In the blood it travels mainly with low-density lipoprotein (LDL). Less than 20 % is associated with high-density lipoprotein HDL. It is an enzyme produced by inflammatory cells and hydrolyzes oxidized phospholipids in LDL. Lp-PLA2 is platelet-activating factor (PAF) acetylhydrolase, a secreted enzyme that catalyzes the degradation of PAF to inactive products by hydrolysis of the acetyl group at the sn-2 position, producing the biologically inactive products LYSO-PAF and acetate.

Gene Full Name: phospholipase A2 group VII

Gene ID: 7941

UniProt: Q13093

Pathways: Peptide Hormone Metabolism