LUM antibody (AA 21-356) (PE)

Catalog No. ABIN8006698

The PE-conjugated Rabbit Polyclonal anti-LUM antibody (ABIN8006698) specifically detects LUM in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for LUM antibody (AA 21-356) (PE) (ABIN8006698)

Target: LUM (Lumican (LUM))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LUM antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-LUM Antibody (PE)

Binding Specificity: AA 21-356

Purpose: Anti-Lumican/LUM Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human ILF2 shares 100% amino acid (aa) sequence identity with mouse?ILF2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NF45/ILF2 recombinant protein (Position: G21-K356). Human ILF2 shares 100% amino acid (aa) sequence identity with mouse?ILF2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LUM

Target: LUM (Lumican (LUM))

Alternative Name: LUM

Background:

Background: Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Gene Full Name: lumican

Gene ID: 4060

UniProt: P51884

Pathways: Glycosaminoglycan Metabolic Process