KDM4A antibody (AA 379-1064) (HRP)

Catalog No. ABIN8006961

The Rabbit Polyclonal anti-KDM4A antibody is suitable to detect KDM4A in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for KDM4A antibody (AA 379-1064) (HRP) (ABIN8006961)

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4A antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-KDM4A Antibody (HRP)

Binding Specificity: AA 379-1064

Purpose: Anti-JHDM3A/JMJD2A/KDM4A Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human JHDM3A/JMJD2A/KDM4A recombinant protein (Position: D379-E1064).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KDM4A

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Alternative Name: KDM4A

Background:

Background: Lysine-specific demethylase 4A is an enzyme that in humans is encoded by the KDM4A gene. This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

Gene Full Name: lysine demethylase 4A

Gene ID: 9682

UniProt: O75164

Pathways: Warburg Effect