KDM6A antibody (AA 391-704) (Biotin)

Catalog No. ABIN8006977

The Biotin-conjugated Rabbit Polyclonal anti-KDM6A antibody (ABIN8006977) specifically detects KDM6A in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for KDM6A antibody (AA 391-704) (Biotin) (ABIN8006977)

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM6A antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-KDM6A Antibody (Biotin)

Binding Specificity: AA 391-704

Purpose: Anti-UTX/KDM6A Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human UTX/KDM6A recombinant protein (Position: A391-A704).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KDM6A

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Alternative Name: KDM6A

Background:

Background: Lysine-specific demethylase 6A also known as Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), is a protein which in humans is encoded by the KDM6A gene. This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene.

Gene Full Name: lysine demethylase 6A

Gene ID: 7403

UniProt: O15550

Pathways: Tube Formation, Warburg Effect