TTDN1 antibody (AA 135-179) (Fluoro550)

Catalog No. ABIN8007189

The Rabbit Polyclonal anti-TTDN1 antibody is suitable to detect TTDN1 in samples from Human. It has been validated for FACS.

Quick Overview for TTDN1 antibody (AA 135-179) (Fluoro550) (ABIN8007189)

Target: TTDN1 (MPLKIP) (M-Phase Specific PLK1 Interacting Protein (MPLKIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTDN1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-TTDN1 Antibody (Fluoro550)

Binding Specificity: AA 135-179

Purpose: Anti-MPLKIP Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MPLKIP shares 97.7% amino acid (aa) sequence identity with mouse MPLKIP.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MPLKIP recombinant protein (Position: E135-C179). Human MPLKIP shares 97.7% amino acid (aa) sequence identity with mouse MPLKIP.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TTDN1

Target: TTDN1 (MPLKIP) (M-Phase Specific PLK1 Interacting Protein (MPLKIP))

Alternative Name: MPLKIP

Background:

Background: The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.

Gene Full Name: M-phase specific PLK1 interacting protein

Gene ID: 136647

UniProt: Q8TAP9