MAD1L1 antibody (AA 362-632) (PE)

Catalog No. ABIN8007304

The PE-conjugated Rabbit Polyclonal anti-MAD1L1 antibody (ABIN8007304) specifically detects MAD1L1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MAD1L1 antibody (AA 362-632) (PE) (ABIN8007304)

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAD1L1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-MAD1L1 Antibody (PE)

Binding Specificity: AA 362-632

Purpose: Anti-MAD1/MAD1L1 Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MAD1 shares 81% amino acid (aa) sequence identity with mouse MAD1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAD1 recombinant protein (Position: L362-A632). Human MAD1 shares 81% amino acid (aa) sequence identity with mouse MAD1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MAD1L1

Target: MAD1L1 (MAD1 Mitotic Arrest Deficient-Like 1 (MAD1L1))

Alternative Name: MAD1L1

Background:

Background: Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene. It is mapped to 7p22.3. MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 can function as a homodimer. It localizes to the centrosome during metaphase and to the spindle midzone and the midbody during anaphase and telophase. MAD1L1 may also play a role in cell cycle control and tumor suppression.

Gene Full Name: mitotic arrest deficient 1 like 1

Sequence Similarities: Belongs to the MAD1 family.

Gene ID: 8379

UniProt: Q9Y6D9

Pathways: M Phase