MAGE-Like 2 antibody (AA 578-847) (APC)

Catalog No. ABIN8007358

The APC-conjugated Rabbit Polyclonal anti-MAGE-Like 2 antibody (ABIN8007358) specifically detects MAGE-Like 2 in FACS. The antibody is reactive with Human samples.

Quick Overview for MAGE-Like 2 antibody (AA 578-847) (APC) (ABIN8007358)

Target: MAGE-Like 2 (MAGEL2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGE-Like 2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-MAGE-Like 2 Antibody (APC)

Binding Specificity: AA 578-847

Purpose: Anti-MAGEL2 Antibody APC Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAGEL2 recombinant protein (Position: Q578-A847).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MAGE-Like 2

Target: MAGE-Like 2 (MAGEL2)

Alternative Name: MAGEL2

Background:

Background: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.

Gene Full Name: MAGE family member L2

Gene ID: 54551

UniProt: Q9UJ55