AANAT antibody (AA 141-207)

Catalog No. ABIN751063

Product Details anti-AANAT Antibody

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Binding Specificity: AA 141-207

Reactivity: Human, Rat, Mouse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AANAT antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat, Sheep

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AANAT

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-AANAT antibody (ABIN751063)

Xiao, Hu, Song, Zhang, Dong, Jiang, Zhang, Yuan, Zhao: "Profile of melatonin and its receptors and synthesizing enzymes in cumulus-oocyte complexes of the developing sheep antral follicle-a potential estradiol-mediated mechanism." in: Reproductive biology and endocrinology : RB&E, Vol. 17, Issue 1, pp. 1, (2019) (PubMed).

Ahn, Park, Kim, Lee, Yan, Yong, Lee, CHoi, Yoo, Hwang, Moon, Shin, Won: "Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord." in: Journal of veterinary science, Vol. 15, Issue 3, pp. 335-42, (2016) (PubMed).

Target Details for AANAT

Target: AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Alternative Name: Aanat (AANAT Products)

Synonyms: DSPS antibody, SNAT antibody, AA-NAT antibody, Nat4 antibody, Nat-2 antibody, Snat antibody, aralkylamine N-acetyltransferase antibody, arylalkylamine N-acetyltransferase antibody, AANAT antibody, Aanat antibody

Background:

Synonyms: DSPS, SNAT, Serotonin N-acetyltransferase, Serotonin acetylase, Aralkylamine N-acetyltransferase, AA-NAT, AANAT

Background: Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.

Gene ID: 15

UniProt: Q16613

Pathways: Photoperiodism