MSL3 antibody (AA 1-498) (Fluoro488)

Catalog No. ABIN8007562

The Fluoro488-conjugated Rabbit Polyclonal anti-MSL3 antibody (ABIN8007562) specifically detects MSL3 in FACS. The antibody is reactive with Human samples.

Quick Overview for MSL3 antibody (AA 1-498) (Fluoro488) (ABIN8007562)

Target: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSL3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-MSL3 Antibody (Fluoro488)

Binding Specificity: AA 1-498

Purpose: Anti-MSL3 Antibody Fluoro488 Conjugated

Predicted Reactivity: Human SLC7A7 shares 90.8%,91.6% amino acid (aa) sequence identity with mouse,rat SLC7A7,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SLC7A7 recombinant protein (Position: M1-D498). Human SLC7A7 shares 90.8% and 91.6% amino acid (aa) sequence identity with mouse and rat SLC7A7, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MSL3

Target: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Alternative Name: MSL3

Background:

Background: Y+L amino acid transporter 1 is a protein that in humans is encoded by the SLC7A7 gene. The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants.

Gene Full Name: MSL complex subunit 3

Gene ID: 10943

UniProt: Q8N5Y2