MPI antibody (AA 2-99) (Fluoro647)

Catalog No. ABIN8007668

This Rabbit Polyclonal antibody specifically detects MPI in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for MPI antibody (AA 2-99) (Fluoro647) (ABIN8007668)

Target: MPI (Mannose Phosphate Isomerase (MPI))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPI antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-MPI Antibody (Fluoro647)

Binding Specificity: AA 2-99

Purpose: Anti-Mannose Phosphate Isomerase/MPI Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human MPI recombinant protein (Position: A2-K99). Human MPI shares 88.8%,86.7% amino acid (aa) sequence identity with mouse,rat MPI,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human MPI recombinant protein (Position: A2-K99). Human MPI shares 88.8% and 86.7% amino acid (aa) sequence identity with mouse and rat MPI, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MPI

Target: MPI (Mannose Phosphate Isomerase (MPI))

Alternative Name: MPI

Background:

Background: Mannose-6 phosphate isomerase (MPI), alternately phosphomannose isomerase (PMI), is an enzyme which facilitates the interconversion of fructose 6-phosphate (F6P) and mannose-6-phosphate (M6P). It also plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. This MPI gene is mapped to 15q24.1.

Gene Full Name: mannose phosphate isomerase

Gene ID: 4351

UniProt: P34949