MPI antibody (AA 2-99) (HRP)

Catalog No. ABIN8007676

The HRP-conjugated Mouse Monoclonal anti-MPI antibody (Clone 11I4) (ABIN8007676) specifically detects MPI in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for MPI antibody (AA 2-99) (HRP) (ABIN8007676)

Target: MPI (Mannose Phosphate Isomerase (MPI))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MPI antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 11I4

Product Details anti-MPI Antibody (HRP)

Binding Specificity: AA 2-99

Purpose: Anti-MPI Antibody (monoclonal, 11I4) HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human MPI recombinant protein (Position: A2-K99). Human MPI shares 88.8%,86.7% amino acid (aa) sequence identity with mouse,rat MPI,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human MPI recombinant protein (Position: A2-K99). Human MPI shares 88.8% and 86.7% amino acid (aa) sequence identity with mouse and rat MPI, respectively.

Isotype: IgG1

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MPI

Target: MPI (Mannose Phosphate Isomerase (MPI))

Alternative Name: MPI

Background:

Background: Mannose-6 phosphate isomerase (MPI), alternately phosphomannose isomerase (PMI), is an enzyme which facilitates the interconversion of fructose 6-phosphate (F6P) and mannose-6-phosphate (M6P). It also plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. This MPI gene is mapped to 15q24.1.

Gene Full Name: mannose phosphate isomerase

Gene ID: 4351

UniProt: P34949