MZB1 antibody (AA 23-189) (Biotin)

Catalog No. ABIN8007846

The Rabbit Polyclonal anti-MZB1 antibody is suitable to detect MZB1 in samples from Human. It has been validated for IHC, WB and ELISA.

Quick Overview for MZB1 antibody (AA 23-189) (Biotin) (ABIN8007846)

Target: MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MZB1 antibody is conjugated to Biotin

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-MZB1 Antibody (Biotin)

Binding Specificity: AA 23-189

Purpose: Anti-MZB1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MZB1 recombinant protein (Position: D23-L189).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MZB1

Target: MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))

Alternative Name: MZB1

Background:

Background: Marginal zone B and B1 cell-specific protein is a protein that in humans is encoded by the MZB1 gene. MZB1, also named as ,PACAP, MGC29506 and pERp1, belongs to the PERP1 family. It is associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. MGC29506(PACAP) may exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. (PubMed: 11350957) MZB1 has 5 isoforms with MW 21kd and 7-13kd.

Gene Full Name: marginal zone B and B1 cell specific protein

Gene ID: 51237

UniProt: Q8WU39

Pathways: Production of Molecular Mediator of Immune Response