Matrilin 3 antibody (C-Term) (Fluoro594)

Catalog No. ABIN8007938

This Rabbit Polyclonal antibody specifically detects Matrilin 3 in FACS. It exhibits reactivity toward Human.

Quick Overview for Matrilin 3 antibody (C-Term) (Fluoro594) (ABIN8007938)

Target: Matrilin 3 (MATN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Matrilin 3 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-Matrilin 3 Antibody (Fluoro594)

Binding Specificity: C-Term

Purpose: Anti-Matrilin 3/MATN3 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Matrilin 3.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Matrilin 3

Target: Matrilin 3 (MATN3)

Alternative Name: MATN3

Background:

Background: MATN3 (Matrilin-3) is a protein that in humans is encoded by the MATN3 gene. This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins is though to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. By fluorescence in situ hybridization, Belluoccio et al. (1998) mapped the human MATN3 gene to chromosome 2p24-p23. Wagener et al. (2000) mapped the mouse Matn3 gene to the proximal end of chromosome 12, linked to the genes Synd1, Apob, Dtnb, and Kif3c. The human homologs of all 5 of these genes map to 2p23, indicating considerable homology of synteny. This protein contains two von Willebrand factor A domains, it is present in the cartilage extracellular matrix and has a role in the development and homeostasis of cartilage and bone. Mutations in this gene result in multiple epiphyseal dysplasia.

Gene Full Name: matrilin 3

Sequence Similarities: Contains 4 EGF-like domains.

Gene ID: 4148

UniProt: O15232