MGP antibody (AA 20-96) (Fluoro488)

Catalog No. ABIN8007969

The Rabbit Polyclonal anti-MGP antibody is suitable to detect MGP in samples from Human. It has been validated for FACS.

Quick Overview for MGP antibody (AA 20-96) (Fluoro488) (ABIN8007969)

Target: MGP (Matrix Gla Protein (MGP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGP antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-MGP Antibody (Fluoro488)

Binding Specificity: AA 20-96

Purpose: Anti-MGP Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MGP shares 84.4%,80.5% amino acid (aa) sequence identity with mouse,rat MGP,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MGP recombinant protein (Position: Y20-F96). Human MGP shares 84.4% and 80.5% amino acid (aa) sequence identity with mouse and rat MGP, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MGP

Target: MGP (Matrix Gla Protein (MGP))

Alternative Name: MGP

Background:

Background: Matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein initially isolated from bovine bone. In addition, MGP is a 10-kD protein produced and secreted by vascular smooth muscle cells and chondrocytes and significantly accumulated in bone, cartilage, and dentin. It is also expressed at high levels in heart, kidney, and lung and is upregulated by vitamin D in bone cells. MGP has a high affinity binding to calcium ions, similar to other Gla-containing proteins. The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization. And this gene is mapped to 12p12.3.

Gene Full Name: matrix Gla protein

Gene ID: 4256

UniProt: P08493