MMP10 antibody (AA 239-476) (FITC)

Catalog No. ABIN8008016

This Rabbit Polyclonal antibody specifically detects MMP10 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MMP10 antibody (AA 239-476) (FITC) (ABIN8008016)

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP10 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-MMP10 Antibody (FITC)

Binding Specificity: AA 239-476

Purpose: Anti-MMP10 Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human MMP10 recombinant protein (Position: Y239-C476). Human MMP10 shares 74.4%,73.9% amino acid (aa) sequence identity with mouse,rat MMP10,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human MMP10 recombinant protein (Position: Y239-C476). Human MMP10 shares 74.4% and 73.9% amino acid (aa) sequence identity with mouse and rat MMP10, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MMP10

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Alternative Name: MMP10

Background:

Background: Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene Full Name: matrix metallopeptidase 10

Gene ID: 4319

UniProt: P09238