ADCY4 antibody (AA 851-1077) (Cy3)

Catalog No. ABIN751171

This Rabbit Polyclonal antibody specifically detects ADCY4 in WB, IF (cc), IF (p). It exhibits reactivity toward Human.

Quick Overview for ADCY4 antibody (AA 851-1077) (Cy3) (ABIN751171)

Target: ADCY4 (Adenylate Cyclase 4 (ADCY4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY4 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ADCY4 Antibody (Cy3)

Binding Specificity: AA 851-1077

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADCY4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADCY4

Target: ADCY4 (Adenylate Cyclase 4 (ADCY4))

Alternative Name: ADCY4

Background:

Synonyms: AC4, Adenylate cyclase 4, adenylate cyclase type 4, Adenylate cyclase type IV, Adenylyl cyclase, ATP pyrophosphate lyase 4, ATP pyrophosphate lyase, ADCY4_HUMAN.

Background: The ADCY4 gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.

Gene ID: 196883

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma