MLANA antibody (AA 1-37) (Fluoro488)

Catalog No. ABIN8008805

This Rabbit Polyclonal antibody specifically detects MLANA in FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for MLANA antibody (AA 1-37) (Fluoro488) (ABIN8008805)

Target: MLANA (Melan A (MLANA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLANA antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-MLANA Antibody (Fluoro488)

Binding Specificity: AA 1-37

Purpose: Anti-Melan-A/MLANA Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Melan-A/MLANA recombinant protein (Position: M1-L37).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MLANA

Target: MLANA (Melan A (MLANA))

Alternative Name: MLANA

Background:

Background: MLANA (Melan-A, also known as MART1, MART-1), located on 9p24.1, is a Protein Coding gene. The gene produces a 13157 Da protein composed of 118 amino acids. MLANA is a hydrophobic transmembrane protein without glycosylation sites highly enriched in early melanosomes. MLANA is expressed in skin and retinae melanocytes and the majority of melanoma tumors, but it is absent from other tissues and tumors. Diseases such as Melanoma In Congenital Melanocytic Nevus and Angiomyolipoma are associated with MLANA. The related pathways of MLANA include NF-kappaB Signaling.

Gene Full Name: melan-A

Gene ID: 2315

UniProt: Q16655