MC4R antibody (C-Term) (Cy3)

Catalog No. ABIN8008848

The Rabbit Polyclonal anti-MC4R antibody is suitable to detect MC4R in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for MC4R antibody (C-Term) (Cy3) (ABIN8008848)

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC4R antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-MC4R Antibody (Cy3)

Binding Specificity: C-Term

Purpose: Anti-MC4-R/MC4R Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MC4-R/MC4R, which shares 88.5% and 80.8% amino acid (aa) sequence identity with mouse and rat MC4-R/MC4R, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MC4R

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Alternative Name: MC4R

Background:

Background: Melanocortin receptor 4 is a protein that in humans is encoded by the MC4R gene. This gene is mapped to 18q21.32. The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.

Gene Full Name: melanocortin 4 receptor

Gene ID: 4160

UniProt: P32245

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour