MEST antibody (AA 21-320) (Biotin)

Catalog No. ABIN8009221

The Biotin-conjugated Rabbit Polyclonal anti-MEST antibody (ABIN8009221) specifically detects MEST in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MEST antibody (AA 21-320) (Biotin) (ABIN8009221)

Target: MEST (Mesoderm Specific Transcript (MEST))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEST antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MEST Antibody (Biotin)

Binding Specificity: AA 21-320

Purpose: Anti-MEST Antibody Biotin Conjugated

Predicted Reactivity: Human MEST shares 97.7%,98.3% amino acid (aa) sequence identity with mouse,rat MEST,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MEST recombinant protein (Position: A21-D320). Human MEST shares 97.7% and 98.3% amino acid (aa) sequence identity with mouse and rat MEST, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MEST

Target: MEST (Mesoderm Specific Transcript (MEST))

Alternative Name: MEST

Background:

Background: Mesoderm-specific transcript homolog protein is a protein that in humans is encoded by the MEST gene. This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.

Gene Full Name: mesoderm specific transcript

Gene ID: 4232

UniProt: Q5EB52