MUT antibody (N-Term) (Fluoro488)

Catalog No. ABIN8009707

The Fluoro488-conjugated Mouse Monoclonal anti-MUT antibody (Clone 2D6) (ABIN8009707) specifically detects MUT in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MUT antibody (N-Term) (Fluoro488) (ABIN8009707)

Target: MUT (Methylmalonyl Coenzyme A Mutase (MUT))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUT antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Clone: 2D6

Product Details anti-MUT Antibody (Fluoro488)

Binding Specificity: N-Term

Purpose: Anti-Methylmalonyl Coenzyme A mutase Antibody (monoclonal, 2D6) Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MUT, different from the related mouse sequence by one amino acid.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MUT

Target: MUT (Methylmalonyl Coenzyme A Mutase (MUT))

Alternative Name: MUT

Background:

Background: Methylmalonyl-CoA mutase (MUT) is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. This gene is mapped to 6p12.3. MUT requires a vitamin B12-derived prosthetic group, adenosylcobalamin (commonly referred to as AdoCbl), to function. And the product of this enzyme, succinyl-CoA, is a key molecule of the TCA cycle.

Gene Full Name: methylmalonyl-CoA mutase

Gene ID: 4594

UniProt: P22033

Pathways: Monocarboxylic Acid Catabolic Process