METTL3 antibody (AA 71-580) (APC)

Catalog No. ABIN8009833

The APC-conjugated Rabbit Polyclonal anti-METTL3 antibody (ABIN8009833) specifically detects METTL3 in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for METTL3 antibody (AA 71-580) (APC) (ABIN8009833)

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-METTL3 Antibody (APC)

Binding Specificity: AA 71-580

Purpose: Anti-METTL3 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human METTL3 recombinant protein (Position: E71-L580).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for METTL3

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Alternative Name: METTL3

Background:

Background: N6-adenosine-methyltransferase 70 kDa subunit (METTL3) is an enzyme that in humans is encoded by the METTL3 gene. It is mapped to 14q11.2. This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Gene Full Name: methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

Gene ID: 56339

UniProt: Q86U44