METTL3 antibody (C-Term) (Fluoro594)

Catalog No. ABIN8009841

The Rabbit Polyclonal anti-METTL3 antibody is suitable to detect METTL3 in samples from Human. It has been validated for FACS.

Quick Overview for METTL3 antibody (C-Term) (Fluoro594) (ABIN8009841)

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL3 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-METTL3 Antibody (Fluoro594)

Binding Specificity: C-Term

Purpose: Anti-METTL3 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human METTL3, which shares 100% and 95.3% amino acid (aa) sequence identity with mouse and rat METTL3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for METTL3

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Alternative Name: METTL3

Background:

Background: N6-adenosine-methyltransferase 70 kDa subunit (METTL3) is an enzyme that in humans is encoded by the METTL3 gene. It is mapped to 14q11.2. This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Gene Full Name: methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

Gene ID: 56339

UniProt: Q86U44