MAVS antibody (AA 34-96) (PE)

Catalog No. ABIN8010616

The PE-conjugated Rabbit Polyclonal anti-MAVS antibody (ABIN8010616) specifically detects MAVS in FACS. The antibody is reactive with Human samples.

Quick Overview for MAVS antibody (AA 34-96) (PE) (ABIN8010616)

Target: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAVS antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-MAVS Antibody (PE)

Binding Specificity: AA 34-96

Purpose: Anti-MAVS Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human MAVS recombinant protein (Position: L34-Q96). Human MAVS shares 72.6%,69.4% amino acid (aa) sequence identity with mouse,rat MAVS,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human MAVS recombinant protein (Position: L34-Q96). Human MAVS shares 72.6% and 69.4% amino acid (aa) sequence identity with mouse and rat MAVS, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MAVS

Target: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Alternative Name: MAVS

Background:

Background: Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity.

Gene Full Name: mitochondrial antiviral signaling protein

Gene ID: 57506

UniProt: Q7Z434

Pathways: Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C