MAVS antibody (N-Term) (Biotin)

Catalog No. ABIN8010619

The Biotin-conjugated Rabbit Polyclonal anti-MAVS antibody (ABIN8010619) specifically detects MAVS in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for MAVS antibody (N-Term) (Biotin) (ABIN8010619)

Target: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAVS antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MAVS Antibody (Biotin)

Binding Specificity: N-Term

Purpose: Anti-MAVS Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at N-terminus of human MAVS.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAVS

Target: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Alternative Name: MAVS

Background:

Background: Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity.

Gene Full Name: mitochondrial antiviral signaling protein

Gene ID: 57506

UniProt: Q7Z434

Pathways: Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C