MTCH2 antibody (AA 1-303) (Biotin)

Catalog No. ABIN8010663

The Rabbit Polyclonal anti-MTCH2 antibody is suitable to detect MTCH2 in samples from Human and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for MTCH2 antibody (AA 1-303) (Biotin) (ABIN8010663)

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTCH2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MTCH2 Antibody (Biotin)

Binding Specificity: AA 1-303

Purpose: Anti-MTCH2 Antibody Biotin Conjugated

Predicted Reactivity: Human MTCH2 shares 93.7% amino acid (aa) sequence identity with mouse MTCH2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MTCH2 recombinant protein (Position: M1-I303). Human MTCH2 shares 93.7% amino acid (aa) sequence identity with mouse MTCH2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MTCH2

Target: MTCH2 (Mitochondrial Carrier 2 (MTCH2))

Alternative Name: MTCH2

Background:

Background: Mitochondrial carrier homolog 2 also known as MTCH2 is a protein which in humans is encoded by the MTCH2 gene. This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target that can produce two isoforms from the same mRNA by use of alternative in-frame translation termination codons.

Gene Full Name: mitochondrial carrier 2

Gene ID: 23788

UniProt: Q9Y6C9