MRPS18B antibody (AA 23-211) (Fluoro488)

Catalog No. ABIN8010731

This Rabbit Polyclonal antibody specifically detects MRPS18B in FACS. It exhibits reactivity toward Human.

Quick Overview for MRPS18B antibody (AA 23-211) (Fluoro488) (ABIN8010731)

Target: MRPS18B (Mitochondrial Ribosomal Protein S18B (MRPS18B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS18B antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-MRPS18B Antibody (Fluoro488)

Binding Specificity: AA 23-211

Purpose: Anti-MRPS18B Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MRPS18B recombinant protein (Position: H23-R211).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MRPS18B

Target: MRPS18B (Mitochondrial Ribosomal Protein S18B (MRPS18B))

Alternative Name: MRPS18B

Background:

Background: 28S ribosomal protein S18b, mitochondrial is a protein that in humans is encoded by the MRPS18B gene. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.

Gene Full Name: mitochondrial ribosomal protein S18B

Gene ID: 28973

UniProt: Q9Y676