MT-ND2 antibody (N-Term) (Biotin)

Catalog No. ABIN8010784

The Biotin-conjugated Rabbit Polyclonal anti-MT-ND2 antibody (ABIN8010784) specifically detects MT-ND2 in WB, IHC and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for MT-ND2 antibody (N-Term) (Biotin) (ABIN8010784)

Target: MT-ND2 (Mitochondrially Encoded NADH Dehydrogenase 2 (MT-ND2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MT-ND2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-MT-ND2 Antibody (Biotin)

Binding Specificity: N-Term

Purpose: Anti-NADH2/Mtnd2 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of rat NADH2/Mtnd2, which shares 80% amino acid (aa) sequence identity with mouse NADH2/Mtnd2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MT-ND2

Target: MT-ND2 (Mitochondrially Encoded NADH Dehydrogenase 2 (MT-ND2))

Alternative Name: Mtnd2

Background:

Background: Mitochondrially encoded NADH dehydrogenase 2 is protein that in humans is encoded by the mitochondrial gene MT-ND2 gene. The ND2 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variants of MT-ND2 are associated with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), Leigh's syndrome (LS), Leber's hereditary optic neuropathy (LHON) and increases in adult BMI.

Gene Full Name: NADH dehydrogenase subunit 2

Gene ID: 26194

UniProt: P11662