MAP4K1 antibody (N-Term) (Biotin)

Catalog No. ABIN8011345

The Biotin-conjugated Rabbit Polyclonal anti-MAP4K1 antibody (ABIN8011345) specifically detects MAP4K1 in WB, ELISA and IHC. The antibody is reactive with Rat samples.

Quick Overview for MAP4K1 antibody (N-Term) (Biotin) (ABIN8011345)

Target: MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4K1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MAP4K1 Antibody (Biotin)

Binding Specificity: N-Term

Purpose: Anti-MAP4K1/HPK1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of rat MAP4K1/HPK1, which shares 88.2% and 100% amino acid (aa) sequence identity with human and mouse MAP4K1/HPK1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAP4K1

Target: MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Alternative Name: Map4k1

Background:

Background: Mitogen-activated protein kinase kinase kinase kinase 1 is a protein kinase that in humans is encoded by the MAP4K1 gene. It is also known as HPK1 (Hematopoietic Progenitor Kinase 1). The protein has been shown to play a role in JNK activation.

Gene Full Name: mitogen activated protein kinase kinase kinase kinase 1

Gene ID: 292763

UniProt: D3Z8I4

Pathways: TCR Signaling, Signaling of Hepatocyte Growth Factor Receptor