MAP4K2 antibody (AA 53-807) (PE)

Catalog No. ABIN8011375

The PE-conjugated Rabbit Polyclonal anti-MAP4K2 antibody (ABIN8011375) specifically detects MAP4K2 in FACS. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for MAP4K2 antibody (AA 53-807) (PE) (ABIN8011375)

Target: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4K2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-MAP4K2 Antibody (PE)

Binding Specificity: AA 53-807

Purpose: Anti-MAP4K2 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MAP4K2 shares 93.4% amino acid (aa) sequence identity with mouse MAP4K2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAP4K2 recombinant protein (Position: D53-H807). Human MAP4K2 shares 93.4% amino acid (aa) sequence identity with mouse MAP4K2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MAP4K2

Target: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Alternative Name: MAP4K2

Background:

Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants.

Gene Full Name: mitogen-activated protein kinase kinase kinase kinase 2

Gene ID: 5871

UniProt: Q12851