MAP4K2 antibody (AA 53-807)

Catalog No. ABIN8011377

The Rabbit Polyclonal anti-MAP4K2 antibody is suitable to detect MAP4K2 in samples from Human, Mouse, Rat and Monkey. It has been validated for WB and ELISA.

Quick Overview for MAP4K2 antibody (AA 53-807) (ABIN8011377)

Target: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4K2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-MAP4K2 Antibody

Binding Specificity: AA 53-807

Purpose: Anti-MAP4K2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human MAP4K2 shares 93.4% amino acid (aa) sequence identity with mouse MAP4K2.

Characteristics: Anti-MAP4K2 Antibody. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat, Monkey.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAP4K2 recombinant protein (Position: D53-H807). Human MAP4K2 shares 93.4% amino acid (aa) sequence identity with mouse MAP4K2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAP4K2

Target: MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

Alternative Name: MAP4K2

Background:

Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants.

Gene Full Name: mitogen-activated protein kinase kinase kinase kinase 2

Molecular Weight: 97 kDa

Gene ID: 5871

UniProt: Q12851